ABSTRACT
Objective To understand the late detection of new HIV/AIDS cases in Changshu City from 2015 to 2019， and to provide scientific basis for AIDS prevention and control. Methods The newly reported HIV/AIDS cases in Changshu City from 2015 to 2019 were collected through the “information system for integrated prevention and treatment of AIDS”. According to the criteria for late detection of HIV/AIDS， the influencing factors of late detection of HIV/AIDS were verified and the relevant epidemiological analysis was carried out. Results A total of 423 cases of HIV/AIDS were reported in Changshu City from 2015 to 2019， and the average incidence rate was 4.33/105. The overall incidence rate did not show a downward trend （χ2trend=3.543， P=0.060）. The incidence rate of males （7.35/105） was higher than that of females （0.93/105）. The trend of incidence rate in males was significantly decreased （χ2trend=6.264， P=0.012）， but it did not have a significant change in females （χ2trend=1.717， P=0.190）. The average annual HIV/AIDS late detection rate was 23.88% （101/423）， with the highest in 2015 （33.68%） and the lowest in 2017 （12.94%）.It showed a valley distribution pattern with first decline and then rise. The difference in HIV/AIDS late detection rate in recent five years was statistically significant （χ2=17.087， P=0.002）. At the end of the report， the proportion of male patients （89.11%） was higher than that of females （10.89%）， and nearly half （46.53%） of the patients were in elderly group aged 50 years old （46.53%）. Patients with local registered residence （58.42%） had higher late detection rate than those with foreign household registration （41.58）. Most the patients were junior high school educated （36.63%）， followed by primary school （26.73%） and senior high school （21.78%）. 68.32% of the patients were married and had a spouse. The top three occupations in patients were farmers （24.75%）， workers （24.75%） and business services （22.77%）， and the other occupations accounted for less than 10%. Most of the HIV positive samples were from other diseases （36.63%）， followed by testing consultation （29.70%） and preoperative testing （16.83%）. 77.23% of the late detection patients had no history of sexual diseases. Late detection in homosexuals （57.43%） were higher than that in heterosexuals （42.57%）. Conclusion The late detection rate of HIV/AIDS in Changshu City in recent five years showed a downward trend and then an upward trend. In the future， we should focus on the elderly， MSM， young students and other high-risk groups of HIV infection， strengthen health education and publicity， expand the scope of HIV testing， improve the ability of early detection， and effectively reduce the risk of HIV transmission.
ABSTRACT
Objective To explore the effect of radiofrequency heating on type Ⅱ collagen expression in a rabbit model of osteoarthritis.Methods Knee osteoarthritis was induced in the right hind legs of 54 male rabbits using modified Hulth modeling.The rabbits were randomly divided into a model group which was not given any special treatment,a Lugua polypeptide group and a radiofrequency hyperthermia group.The Lugua polypeptide group was injected with Lugua polypeptide;the radiofrequency hyperthermia group was treated with radiofrequency irradiation.Six,12 and 18 days after the treatment,the morphological condition of the rats' right femoral medial condyle cartilages were evaluated using modified Mankins scoring and the type Ⅱ collagen content of the cartilage was detected using a quantitative PCR technique.Results At the same time points after treatment,the average Mankins scores were decreased in all the 3 groups,with that of the model group was significantly higher than those of both of the other groups,and the radiofrequency hyperthermia group's average score was significantly better than that of the Lugua polypeptide group.The average type Ⅱ collagen content was significantly increased in all the 3 groups to various extent (the radiofrequency hyperthermia group ＞ Lugua polypeptide group ＞ model group).For the radiofrequency hyperthermia group,the average Mankins score decreased significantly and the average type Ⅱ collagen content increased significantly as the treatment continued.Conclusion Radiofrequency hyperthermia is superior to Lugua polypeptide for treating knee osteoarthritis,at least in rabbits.Its therapeutic effectiveness may be related to a significant increase of type Ⅱ collagen in the cartilage.
ABSTRACT
Objective: To study the nursing of patients with morbid obesity treated with laparoscopic vertical banded gastroplasty (LVBG). Methods: Before operation, obese degree, obesity-related conditions and mental states were examined routinely. Monitoring of respiratory tract, observing operative complications and instructing of diets were done after operation. Results: Among 6 patients, 5 were at the third degree of obese, one was at second. In obesity-related conditions, 4 patients had hypertension and acantha derma, 1 had arthritis, and all had respiratory sleeping syndrome. The operations were all successful. The food amount food and body weight both decreased significantly 1 month after operation. The common operative complications were mild bleeding (1 case), shoulder-back pain (1 case), nausea and vomiting (5 cases). Diet principle was high protein, low energy, liquid food was the first choice. Conclusion: Observing and preventing respiratory sleeping syndrome are the main points of postoperative cares. Instructing patients to establish correct diet habit is the key to reach the best efficacy of LVBG.